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5 Amino 1mq
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5-Amino-1MQ (5-amino-1-methylquinolinium, molecular formula C10H11N2+) is a cell-permeable small-molecule quinolinium derivative. In laboratory and in-vitro settings it is studied as a selective, substrate-competitive inhibitor of nicotinamide N-methyltransferase (NNMT). By blocking NNMT, it prevents the depletion of intracellular NAD+ stores, making it a tool compound for cellular energy metabolism, mitochondrial biogenesis and metabolic regulatory pathway research.
Laboratory Research Focus
Researchers use 5-Amino-1MQ in cell-culture models to examine how methyl-group flux feeds into NAD+ availability and downstream mitochondrial function. Treated and untreated cultures are compared under controlled nutrient conditions, with chromatographic retention and mass-spectral identity verified against a reference standard before experimental use.
- NAD+ homeostasis Used to probe NNMT-mediated NAD+ consumption and its effect on cellular redox state.
- Mitochondrial biogenesis Studied in models linking NAD+ availability to mitochondrial mass and function.
- Metabolic signaling Applied in cell-culture models of metabolic regulation and substrate utilization.
5 Amino 1mq Research Compound
Why BondPep
- Third-party analytical release Every batch runs reverse-phase HPLC with UV detection and ESI-MS identity check by an independent laboratory before it enters inventory.
- Lot records retained online Each vial links to its own batch number; the corresponding HPLC and ESI-MS record is available in the lot lookup page.
- Cold-chain handled Material is climate-controlled from receipt to dispatch, with insulated packaging for temperature-sensitive orders.
- Same-day dispatch In-stock orders leave the facility within 24 hours on business days, tracked to your destination.
Reconstitution & Storage
Reconstitute with sterile bacteriostatic water before laboratory use. Allow the diluent to reach room temperature and inject it slowly down the inner vial wall; do not shake or vortex. Roll the vial gently until the solution is clear and uniform.
Store unopened lyophilized powder at −20°C, protected from light. Once reconstituted, keep refrigerated at 2–8°C and use promptly. Handle with appropriate PPE in a certified laboratory setting.
Product Specifications
- Nomenclature 5 Amino 1mq, Weight Loss research compound
- Package 10-vial box, sealed glass vial
- Physical form White lyophilized powder
- Purity analytics ≥99% (third-party verified)
- Preparation Reconstitute with bacteriostatic water before laboratory use
- Storage −20°C lyophilized; 2–8°C after reconstitution


